Blend the watermelon cubes until smooth.

Strain the watermelon juice into a bowl to remove pulp.

In a cocktail shaker, combine the strained watermelon juice, tequila, lime juice, and agave syrup.

Add ice and shake well until chilled.

Rim glasses with salt and fill with ice.

Strain the cocktail mixture into the prepared glasses.

Garnish with lime wedges.